Service — Clinical Trial Connection
Huntington's Disease Clinical Trials Connection at No Cost
Finding the right Huntington's disease clinical trial can feel overwhelming because each study has its own eligibility criteria, location requirements, research goals, and timeline. HD Genetics helps simplify the process by learning more about YOU on a simple phone call and making recomendations and introductions based on your personal interests.
Enrolling Studies
Active right now
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Always. No fees, ever.
All HD Families
Gene-positive, negative, at-risk.
HD Partnerships
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The Most Active Year in HD Research History
For decades, families affected by Huntington's disease have waited for breakthroughs. In 2026, as many as five pharmaceutical and biotech companies are actively enrolling participants in HD clinical trials across the United States and Canada - alongside many observational studies tracking the natural history of the disease. Every participant, whether gene-positive, gene-negative, or at-risk contributes to research that could change the future for the entire HD community.
Huntington's Disease Studies Enrolling Now
Below are the HD clinical and observational studies actively recruiting across the United States. Study availability changes often — new trials open, others close — so this list is updated regularly.
Last updated: August 2026 · Eligibility details are summaries only — final qualification is confirmed by each study site.
INVEST-HD
Novartis (formerly PTC) - Phase 3
Partner Study- U.S. sites:
- ~65 sites across USA
- Administration:
- Oral pill
- Age range:
- Ages 24–70 (at study start)
- Qualifications:
- Confirmed HD diagnosis / gene-positive, some movement symtpoms
HD Genetics Notes
Study site locations will slowly start opening from May 2026 through the end of the year. Please reach out and we can connect to you trial coordinators at open sites.
PRECISE-HD
Prilenia / Ferrer - Phase 3
- U.S. sites:
- ~25 sites across USA
- Administration:
- Oral pill
- Age range:
- Ages 24–65 (at study start)
- Qualifications:
- Confirmed HD diagnosis / gene-positive, some movement symptoms, some cognitive syptoms
HD Genetics Notes
Study site locations are coming available as of August 2026 and will continue to come available through the end of the year. Please reach out and we can connect you to a trial coordinator at open sites.
FALCON-HD
Skyhawk Therapeutics - Phase 2/3
- U.S. sites:
- ~5 sites across USA
- Administration:
- Oral pill
- Age range:
- Ages 24–65 (at study start)
- Qualifications:
- Confirmed HD diagnosis / gene-positive with 40+ CAGs, some movement symptoms, some cognitive syptoms
HD Genetics Notes
Study site locations in the USA are estimated to be announced in August - October 2026. Fill out an intake form and we can keep you posted on when these are announced.
Enroll-HD
CHDI Foundation
- U.S. sites:
- 30+ sites nationwide
- Administration:
- Observational — no study drug
- Age range:
- Ages 18+
- Qualifications:
- Open to gene-positive, gene-negative & at-risk family members
HD Genetics Notes
This is a once a year in-person visit, that everyone should consider participating in. The study has an emphasis for more individuals aged 18-40 years old.
MEND-HD
University of Rochester / FDA-funded
- U.S. sites:
- Fully virtual — no site visits required
- Administration:
- Observational — wearable sensors, virtual visits
- Age range:
- Ages 25–65
- Qualifications:
- Genetically confirmed HD diagnosis, early-to-middle stage (HD-ISS Stage 2 or mild/moderate Stage 3)
HD Genetics Notes
As of Augus
HD CLARITY
CHDI Foundation / Multi-Site Consortium
- U.S. sites:
- Denver, Washington DC, Nashville, Houston and Baltimore.
- Administration:
- Observational — cerebrospinal fluid (CSF) collection via lumbar puncture/spinal tap
- Age range:
- Ages 18+
- Qualifications:
- Gene-positive HD individuals and healthy controls; no study drug involved
HD Genetics Notes
Must participate in Enroll-HD at one of these sites to also do HD Clarity. Travel expenses are covered by the study.
REGEN4HD - Human Neural Stem Cells
REGEN4HD Research Team - Phase 1b/2a
- U.S. sites:
- UC Irvine California (only)
- Administration:
- Clinical — contact study team for administration details
- Age range:
- Contact study team for eligibility
- Qualifications:
- Huntington's disease — contact HD Genetics for full eligibility criteria
HD Genetics Notes
As of Augus
Set up a call with HD Genetics to learn more and get connected to studies.
FREE · NO OBLIGATION · ALL 50 STATES
Schedule HereHow HD Clinical Trial Connection Works
A simple, supportive process designed around you. There's no rush, no commitment, and no cost.
Fill Out the Intake Form
A short questionnaire to tell us a bit about your situation — gene status (if known), location, and your interests in HD research. Takes about 5 minutes.
Schedule a Call With Our Team
After your intake form, our team reaches out to find a time that works for you. You'll book a virtual phone or video conversation — no commitment, no cost.
Have a Conversation With HD Genetics
Meet virtually with B.J. Viau (View), our Founder and HD research expert.
Get Customized Trial Connections
Based on your interests, location, and qualifications, we provide personalized connections to clinical and observational studies that may be a fit, drawing on our partnership with the Huntington Study Group (HSG).
Stay Connected as New Trials Emerge
No rush, no commitment, no cost — ever. Our team is here whenever you're ready.
Everything That's Included in Your Trial Connection
One free service. Five full benefits. No fees, no insurance billing, no obligation to participate in anything.
Initial Consultation
A free, no-pressure conversation to understand your situation, your goals, and your comfort level with research participation.
HD Research Education
Plain-language walkthrough of the current HD research landscape — clinical trials, observational studies, and what each one involves.
Personalized Trial Matching
We identify studies that may be a fit based on your location, health history, gene status, and personal preferences.
Direct Site Introductions
We connect you directly with research teams at study sites — no cold calls, no lost referrals, no navigating the system alone.
Ongoing Updates & Outreach
We will do the work to stay up to date on HD trials and reach out to you when new opportunities arise, so you can focus on living your life.
Understanding the Types of HD Studies
Not all research looks the same. Here are the main categories of HD studies you may be matched with — each with a different goal, time commitment, and level of involvement.
Interventional Trials
Disease-Modifying Therapy
Clinical trials testing whether new treatments can slow, halt, or reverse HD progression. Involve regular visits, monitoring, and sometimes a placebo group.
Observational Studies
Natural History Tracking
No medication, no intervention. Researchers track how HD develops over time. Often the easiest way to contribute — sometimes just an annual visit or questionnaire.
Biomarker Research
Early Detection Studies
Researchers collect samples (blood, saliva, imaging) to identify biological markers that signal HD progression — often before symptoms appear.
Symptom Management Trials
Symptom-Focused Treatment
Clinical trials testing therapies designed to manage specific HD symptoms — such as chorea, mood changes, or cognitive challenges.
Whatever your situation, your counselor will walk you through which study types fit you best — and there's no obligation to enroll in any of them.
Your Trial Connection Lead
B.J. Viau (View) — Personally Guiding You Through HD Research
Trial Connection Lead, HD Genetics
B.J. founded HD Genetics from a place of lived experience — and that same experience guides every Clinical Trial Connection conversation. Since his mother's diagnosis with HD in 1995, B.J. has spent three decades inside the HD community, including 15+ years working in the pharmaceutical industry where he played a role in the launch of the first FDA-approved medicine for Huntington's chorea.
What makes B.J. uniquely positioned to help connect you to research is that he has personally participated in multiple HD studies himself — including PREDICT-HD, PREVENT-HD, ENROLL-HD, and HD Clarity. He understands what enrollment feels like from the participant's side: the questions you'll have, the time commitment involved, the emotional considerations, and what to expect at study sites.
Reach B.J. directly about HD research opportunitiesIs HD Clinical Trial Connection Right for You?
You're a Good Fit If:
- You're part of an HD family — gene-positive, gene-negative, at-risk, or related
- You're 18 years of age or older
- You're living in the United States or Canada
- You're curious about HD research — even if you're not sure you want to participate
This service is completely free regardless of whether you decide to enroll in any study. There's no obligation, ever.
HD Clinical Trial FAQs
Quick answers to the most common questions about participating in Huntington's disease research.
Take the Next Step on Your HD Journey
Whether you're ready for testing, exploring clinical trials, or just want to talk — our team is here for you, on your timeline.
Get Connected — FreeFREE · NO OBLIGATION · ALL 50 STATES